Abstract Search

ea0081p59 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Impaired glucose homeostasis in a tau knock-in mouse model

Benderradji Hamza , Kraiem Sarra , Emilie Courty , Eddarkaoui Sabiha , Cyril Bourouh , Emilie Faivre , Laure Rolland , Emilie Caron , Melanie Besegher , Frederik Oger , Theo Boschetti , Kevin Carvalho , Bryan Thiroux , Thibaut Gauvrit , Emilie Nicolas , Victoria Gomez-Murcia , Anna Bogdanova , Antonino Bongiovanni , Anne Tailleux , Steve Lancel , Kadiombo Bantubungi , Nicolas Sergeant , Jean-Sebastien Annicotte , Luc Buee , Didier Vieau , David Blum , Valerie Buee-Scherrer

Introduction: Alzheimer disease (AD) is the leading cause of dementia. While impaired glucose homeostasis has been shown to increase AD risk and pathological loss of tau function, the latter has been suggested to contribute to the emergence of the glucose homeostasis alterations observed in AD patients. However, the links between tau impairments and glucose homeostasis, remains unclear.Objective: In order to better understand the links between tau and gl...

0 shares

Endocrine Abstracts

Impaired glucose homeostasis in a tau knock-in mouse model

BiosciAbstracts